High-frequency oscillations pinpoint the seizure-onset zone
نویسندگان
چکیده
منابع مشابه
High-frequency Oscillations and the Seizure Onset Zones in Neocortical Epilepsy
BACKGROUND To study the characters of high-frequency oscillations (HFOs) in the seizure onset zones (SOZ) and the nonseizure onset zones (NSOZ) in the electrocorticography (ECoG) of patients with neocortical epilepsy. METHODS Only patients with neocortical epilepsy who were seizure-free after surgery as determined with ECoG were included. We selected patients with normal magnetic resonance im...
متن کاملClinical impact of a high-frequency seizure onset zone in a case of bitemporal epilepsy.
High-frequency activity has been described as having a role in the initiation of epileptic seizures. The case of a patient with refractory bitemporal epilepsy is presented. Extraoperative monitoring with depth and subdural electrodes revealed an ictal pattern with a build-up of high-frequency (> 80 Hz) activity originating in the cortex, with spread to both hippocampi. This observation was only...
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PURPOSE Research into epileptic networks has recently allowed deeper insights into the epileptic process. Here we investigated the importance of individual network nodes for seizure dynamics. METHODS We analysed intracranial electroencephalographic recordings of 86 focal seizures with different anatomical onset locations. With time-resolved correlation analyses, we derived a sequence of weigh...
متن کاملHigh-frequency oscillations and seizure generation in neocortical epilepsy.
Neocortical seizures are often poorly localized, explosive and widespread at onset, making them poorly amenable to epilepsy surgery in the absence of associated focal brain lesions. We describe, for the first time in an unselected group of patients with neocortical epilepsy, the finding that high-frequency (60-100 Hz) epileptiform oscillations are highly localized in the seizure onset zone, bot...
متن کاملMethods for Detecting High-Frequency Oscillations in Ongoing Brain Signals: Application to the Determination of Epileptic Seizure Onset Zones
METHODS FOR DETECTING HIGH-FREQUENCY OSCILLATIONS IN ONGOING BRAIN SIGNALS: APPLICATION TO THE DETERMINATION OF EPILEPTIC SEIZURE ONSET ZONES Chiran D. Doshi, B.S. Marquette University, 2011 Epilepsy is a neurological disorder with varied expression. Patients with focal onset seizures that are resistant to medications can benefit from ablative surgery. However, localization of the seizure onset...
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ژورنال
عنوان ژورنال: Nature Reviews Neurology
سال: 2011
ISSN: 1759-4758,1759-4766
DOI: 10.1038/nrneurol.2011.127